Chip Projects

1 Spin - off Company (DigiFluidic Biotech Ltd.)
10 RSC Lab on a Chip (4 cover articles)
1 RSC Journal of Material Chemistry C
2 RSC Analyst
1 RSC Advances
1 Nature Communications
1 Nature Publishing Group - Microsystems & Nanoengineering
2 Nature Publishing Group - Scientific Reports
1 Elsevier Biosensors and Bioelectronics
2 Elsevier Sensors and Actuators B: Chemical
1 ACS Analytical Chemistry
1 ACS Sensors (1 cover article)
1 Springer Microfluidics and Nanofluids
1 Springer Biomedical Microdevices
1 Oxford Bioinformatics
1 AIP Advances
1 IET Micro & Nano Letters

Drug Screening on Digital Microfluidics for Cancer Precision Medicine

Jiao Zhai, Yingying Liu, Weiqing Ji, Xinru Huang, Ping Wang, Yunyi Li, Haoran Li, Ada Hang - Heng Wong, Xiong Zhou, Ping Chen, Lianhong Wang, Ning Yang, Chi Chen, Haitian Chen, Pui - In Mak, Chu - Xia Deng, Rui Martins, Mengsu Yang, Tsung - Yi Ho, Shuhong Yi*, Hailong Yao*, Yanwei Jia*

[Nature Communications'24]

A syndromic diagnostic assay on macrochannel - to - digital microfluidic platform for automatic identification of multiple respiratory pathogens

Cheng Dong, Fei Li, Yun Sun, Dongling Long, Chunzhao Chen, Mengyan Li, Tao Wei, Rui P Martins, Tianlan Chen and Pui - In Mak

[RSC Lab on a Chip'24]

Absolute Quantification of Nucleic Acid on Digital Microfluidics Platform Based on Superhydrophobic–Superhydrophilic Micropatterning

Li Meng, Mingzhong Li, Zhenyu Xu, Aman Lv, Yanwei Jia, Meiwan Chen, Pui - In Mak, Rui P. Martins, Man - Kay Law

[Elsevier Sensors and Actuators B: Chemical'24]

Sub - 5 - Minute Ultrafast PCR using Digital Microfluidics

L. Wan, M. Li, M. - K. Law, P. - I. Mak, and R. P. Martins, Y. Jia

[Elsevier Biosensors and Bioelectronics'23]

One - shot High - resolution Melting Curve Analysis for KRAS Point - Mutation - Discrimination on a Digital Microfluidics Platform

M. Li, L. Wan, M. - K. Law, L. Meng, Y. Jia, P. - I. Mak, and R. P. Martins

[RSC Lab on a Chip'22, cover article]

Ratiometric fluorescence analysis for miR - 141 detection with hairpin DNA - templated silver nanoclusters

M. Li, R. Shen, H. Li, Y. Jia, P. - I. Mak, and R. P. Martins

[RSC Journal of Material Chemistry C'22]

Cancer Drug Screening with On - Chip Multi - Drug Dispenser in Digital Microfluidics

J. Zhai, C. Li, H. Li, S. Yi, N. Yang, K. Miao, C. Deng, Y. Jia, P. - I. Mak, and R. P. Martins

[RSC Lab on a Chip'22, inner cover article]

Temperature Tolerance Electric Cell - Substrate Impedance Sensing (ECIS) for Joint Assessment of Cell Viability and Vitality

N. Yang, W. Hui, S. Dong, X. Zhang, L. Shao, Y. Jia, P. - I. Mak, and R. P. Martins

[ACS Sensors'21, inner cover article]

Turning on/off satellite droplets for flexible sample delivery on digital microfluidics

H. Li, R. Shen, C. Dong, T. Chen, Y. Jia, P. - I. Mak, and R. P. Martins

[RSC Lab on a Chip'20, inner cover article]

Clip - to - Release on Amplification (CROA): a Novel DNA Amplification Enhancer on and off Microfluidics

R. Shen, Y. Jia, P. - I. Mak, and R. P. Martins

[RSC Lab on a Chip'20, back cover article]

Portable NMR with Parallelism

K. - M. Lei, D. Ha, Y. - Q. Song, R. Westervelt, R. P. Martins, P. - I. Mak, and D. Ham

[ACS Analytical Chemistry'20]

Digital Microfluidic System with 3D Microstructures for Single - Cell Culture

J. Zhai, H. Li, A. H. - H. Wong, C. Dong, S. Yi, Y. Jia, P. - I. Mak, C. Deng, and R. P. Martins

[Nature Publishing Group - Microsystems & Nanoengineering'20]

Demo Video 1 and Demo Video 2

Hydrodynamic - flow - enhanced rapid mixer for isothermal DNA hybridization kinetics analysis on digital microfluidics platform

M. Li, C. Dong, M. - K. Law, Y. Jia, P. - I. Mak, and R. P. Martins

[Elsevier Sensors and Actuators B: Chemical'19]

Demo Video 1 and Demo Video 2

LampPort - a handheld digital microfluidic device for loop - mediated isothermal amplification (LAMP)

L. Wan, J. Gao, T. Chen, C. Dong, H. Li, Y. - Z. Wen, Z. - R. Lun, Y. Jia, P. - I. Mak, and R. P. Martins

[Springer Biomedical Microdevices'19]

Demo Video

Exploring the Behavior of Water Nanodroplet on a Coplanar Electrowetting - on - Dielectric: A Molecular Dynamics Approach

H. K. Chan, P. - I. Mak, and S. W. I. Siu

[IET Micro & Nano Letters'17]

3D Microblade Structure for Precise and Parallel Droplet Splitting on Digital Microfluidic Chips

C. Dong, Y. Jia, J. Gao, T. Chen, P. - I. Mak, M. - I Vai, and R. P. Martins

[RSC Lab on a Chip'17]

Demo Video

A Digital Microfluidic System for Loop - mediated Isothermal Amplification and Sequence - specific Pathogen Detection

L. Wan, T. Chen, J. Gao, C. Dong, A. H. - H. Wong, Y. Jia, P. - I. Mak, C. - X. Deng and R. P. Martins

[Nature Publishing Group - Scientific Reports'16]

Demo Video

CMOS Biosensors for In Vitro Diagnosis - Transducing Mechanisms and Applications

K. - M. Lei, P. - I. Mak, M. - K. Law and R. P. Martins

[RSC Lab on a Chip'16]

Sub - 7 - Second Genotyping of Single - Nucleotide Polymorphism by High - Resolution Melting Curve Analysis on a Thermal Digital Microfluidic Device

T. Chen, Y. Jia, C. Dong, J. Gao, P. - I. Mak, and R. P. Martins,

[RSC Lab on a Chip'16]

Demo Video

Drug Screening for RSC Lab on a Chip'16

A. H. - H. Wong, H. Li, Y. Jia, P. - I. Mak, R. P. Martins, Y. Liu, C. M. Vong, H. C. Wong, P. K. Wong, H. Wang, H. Sun, C. - X. Deng

[Nature Publishing Group - Scientific Reports'16]

Demo Video

Cancer Cell Lines and Human Primary Tumors Using Droplet Microfluidics

A. - H. H. Wong, H. Li, Y. Jia, P. - I. Mak, R. P. Martins, Y. Liu, C. M. Vong, H. C. Wong, P. K. Wong, H. Wang, H. Sun, C. - X. Deng

[Nature Publishing Group - Scientific Reports'16]

Demo Video

A Palm - Size μNMR Relaxometer Using a Digital Microfluidic Device and a Semiconductor Transceiver for Chemical/Biological Diagnosis

K. - M. Lei, P. - I. Mak, M. - K. Law and R. P. Martins

[RSC Analyst'15]

Demo Video

On the Droplet Velocity and Electrode Lifetime of Digital Microfluidics: Voltage Actuation Techniques and Comparison

C. Dong, T. Chen, J. Gao, Y. Jia, P. - I. Mak, M. - I Vai and R. P. Martins

[Springer Microfluidics and Nanofluids'15]

Demo Video

Adhesion Promoter for Multi - dielectric - layer on Digital Microfluidic Chip

J. Gao, T. Chen, C. Dong, Y. Jia, P.-I. Mak, M.-I Vai and R. P. Martins

[RSC Advances'15]

Demo Video

NMR - DMF: a Modular Nuclear Magnetic Resonance - Digital Microfluidics System for Biological Assays

K.-M. Lei, P.-I. Mak, M.-K. Law and R. P. Martins

[RSC Analyst'14]

Natural Discharge after Pulse and Cooperative Electrodes to Enhance Droplet Velocity in Digital Microfluidics

T. Chen, C. Dong, J. Gao, Y. Jia, P.-I. Mak, M.-I Vai and R. P. Martins

[AIP Advances'14]

Demo Video

Construction of a Microfluidic Chip for LATE - PCR Amplification and Detection of Single - Stranded DNA using Dried - Down Reagents

Y. Jia, P.-I. Mak, C. Massey, R. P. Martins and L. J. Wangh

[RSC Lab on a Chip'13]

An Intelligent Digital Microfluidic System with Fuzzy - Enhanced Feedback for Multi - Droplet Manipulation

J. Gao, X. Liu, T. Chen, P.-I. Mak, Y. Du, M.-I Vai, B. Lin and R. P. Martins

[RSC Lab on a Chip'13]

Demo Video

Multidisciplinary Projects